Centro3R | Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca

Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca

REFINEMENT

improving experimental design and methods to alleviate or minimise pain, suffering or distress in animals

REPLACEMENT

substitution of procedures on animals with alternative methods of equivalent or better validity and translational value

REDUCTION

reducing the number of animal used in scientific procedures

Publications

A miniaturized multicellular platform to mimic the 3D structure of the alveolar-capillary barrier

Language Undefined

Molte malattie colpiscono gli alveoli e l’efficacia dei trattamenti medici e delle terapie farmaceutiche è ostacolata dalla mancanza di modelli preclinici in grado di ricreare in vitro le malattie.

DOI:

https://doi.org/10.3389/fbioe.2024.1346660

Targeted lipid-coated ZnO nanoparticles coupled with ultrasound: A sonodynamic approach for the treatment of osteosarcoma as 3D spheroid models

Language Undefined

Il cancro alle ossa è una malattia rara con opzioni terapeutiche limitate.

DOI:

https://www.sciencedirect.com/science/article/pii/S2352492824018075?via%3Dihub

The Multifunctional Purposes of Ultrasound in 3D Models

Language Undefined

DOI:

doi/10.1002/adtp.202400161

Toxicity and inflammatory potential of mineral fibres: The contribute of released soluble metals versus cell contact direct effects

Language IT

Asbestos fibres have been considered an environmental hazard for decades. However, little is known about the attempts of circulating immune cells to counteract their toxicity.

DOI:

doi.org/10.1002/jat.4610