Programma Convegno

Draft programme

20 June 2019

8.30 - 9.30	Registration
9.30 - 10.00	Opening Ceremony
	Welcome addresses Prof. Paolo Comanducci and Rectors of affiliated universities
10.00 - 10.50	*Topic: Keynote*
	Arti Ahluwalia (Centro 3R and UNIPI) – Introductory and welcome remarks
	Keynote Lecture: Susanna Louhimies (DG Environment) –Directive 2010/63/EU – progress, challenges and future directions
10.50 - 11.20	Coffee Break
11.20 - 12.20	*Topic: Involvement of national and international Institutions in 3R implementation.*
	Ugo Santucci, Ministero della Salute, Italy
	Delegato MIUR
	Rodolfo Lorenzini, Istituto Superiore di Sanità, Italy
	Adelaide Dura (Joint Research Centre - JRC) – Three Rs in education and training
12.20 - 13.20	*Topic: Reduction and Refinement: scientific, ethical and legal issues*
	Angelo Gazzano (UNIPI) – Refinement of laboratory animal welfare
	Michele Panzera (Università di Messina) – Neurophysiological models of animal sentience
	Franco Manti (UNIGE) – For an ethical experimentation: Moral arguments in support of 3Rs.
13.20 - 14.30	Light Lunch and Young Poster Session
14.30 - 15.30	*Topic: Companies in supporting 3R principles*
	Salvatore Simmini (StemCell Technologies) – Discovering Organoids: The Journey Of 3D Culture Systems
	Francesco Nevelli (Senior Scientist, MerckGroup) – Renewing Potency Assays: moving forward from traditional methods
	Nikolas Gaio (BI/OND) – Versatile organ on chip platforms
	Alberto Manganaro (Kode Chemoinformatics) – QSAR models and their practical use, the experience of Kode
15.30 - 16.10	*Topic: In Silico Models: Toxicology & Efficacy of Drugs, and Chemicals*
	Marco A. Deriu (POLITO) – Computational molecular modelling as replacement technology in rational drug design & discovery
	Gaetano Valenza (UNIPI) – From statistical uncertainty to machine learning through in-silico models
16.10 - 17.10	*Topic: Application of Reduction principles in animal testing*
	Raffaella Colombo (UNIPV) – A new in vitro* gastrointestinal system to evaluate the effect of exogenous molecules*
	Luigi Preziosi (POLITO) – How can Mathematical Modelling Support Cancer Research
	Manuela Marcoli (UNIGE ) – Centr 3R organ and Tissue Sharing Project
17.10 - 17.50	*Topic: Application of Refinement principles in animal testing*
	Gianfranco Beniamino Fiore (POLIMI) – Advanced culture systems for ex-vivo vascular tissue conditioning
	Michele Conti (UNIPV) – Biomechanical simulations and 3D printing for endovascular device testing
	Giovanni Nicoletti ( UNIPV) – Platelet rich plasma enhancement of ex-vivo human skin cultures
17.50- 20.00	Cocktails and poster evaluation

21 June 2019

9.30 - 9.50	Keynote Lecture: Chantra Eskes (Swiss 3R Center) – Promoting 3Rs implementation through research, education, communication
9.50 - 10.50	*Topic: Disease Models Using Human Cells, Tissues and Organs*
	Barbara Parodi (IRCSS San Martino Genova) – Biobanking and biomolecular resource research infrastructure: the Italian node.
	Simone Lapi (Biobanca Pisa) – Pisa Biobank and Tuscany Regional Biorepository
	Gianluca Ciardelli (POLITO) – On the transferability of tissue engineering technologies to the design of tissue models
10.50-11.20	Coffee Break and Young Poster Session
11.20 –12.10	*Round table - Role of 3R Centers*
12.10-12.50.	Young Poster Session Award
12.50-14.00	Light Lunch
14.00- 15.20	*Topic: Application of Replacement in research*
	Maria Grazia Cascone (UNIPI) –Tissue engineered constructs for the replacement of laboratory animals
	Sara Mantero (POLIMI) – Bioreactors as physiological-like in vitro models
	Paola Petrini (POLIMI) – Hydrogel-based platforms to mimic in vivo drug diffusion: a multicenter research
	Susi Burgalassi (UNIPI) – Reconstituted epithelial corneal tissues for evaluation of drug delivery
15.20 -16.20	*Topic: Commitment of Centro 3R in University training*
	Arti Ahluwalia (UNIPI) – Inserting 3Rs in core curricula, hurdles and achievements
	Anna Maria Bassi (UNIGE) –Teaching and Training in Substitutive Approaches to Animal Testing: Commitment of UNIGE
	Valeria Chiono (POLITO) – Approaching 3R teaching in biomedical engineering
	Andrea Aliverti (POLIMI) – Ethical issues in Ph.D. training at PoliMI
16.20 - 18.00	*Centro 3R Council Meeting*

Programma Convegno

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